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Structural Changes of Envelope Proteins During Alphavirus Fusion
Alphaviruses are enveloped RNA viruses that have a diameter of about 700 Å and can be lethal human pathogens1 (Fig. 1). Entry of virus into host cells by endocytosis is controlled by two envelope glycoproteins, E1 and E2. The E2-E1 heterodimers form 80 trimeric spikes on the icosahedral virus surfac...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057476/ https://www.ncbi.nlm.nih.gov/pubmed/21124457 http://dx.doi.org/10.1038/nature09546 |