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The pluripotency factor, Oct4, interacts with Ctcf and also controls X-chromosome pairing and counting

Pluripotency of embryonic stem (ES) cells is controlled by defined transcription factors1,2. During differentiation, mouse ES cells undergo global epigenetic reprogramming, as exemplified by X-chromosome inactivation (XCI) whereby one female X-chromosome is silenced to achieve gene dosage parity bet...

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Detalles Bibliográficos
Autores principales: Donohoe, Mary E., Silva, Susana S., Pinter, Stefan F., Xu, Na, Lee, Jeannie T.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057664/
https://www.ncbi.nlm.nih.gov/pubmed/19536159
http://dx.doi.org/10.1038/nature08098