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The NDC80 complex proteins Nuf2 and Hec1 make distinct contributions to kinetochore–microtubule attachment in mitosis

Successful mitosis requires that kinetochores stably attach to the plus ends of spindle microtubules. Central to generating these attachments is the NDC80 complex, made of the four proteins Spc24, Spc25, Nuf2, and Hec1/Ndc80. Structural studies have revealed that portions of both Hec1 and Nuf2 N ter...

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Detalles Bibliográficos
Autores principales: Sundin, Lynsie J.R., Guimaraes, Geoffrey J., DeLuca, Jennifer G.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057701/
https://www.ncbi.nlm.nih.gov/pubmed/21270439
http://dx.doi.org/10.1091/mbc.E10-08-0671