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A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes

 The mechanism by which transforming growth factor-β (TGFβ) regulates differentiation in human epidermal keratinocytes is still poorly understood. To assess the role of Smad signaling, we engineered human HaCaT keratinocytes either expressing small interfering RNA against Smads2, 3, and 4 or overexp...

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Detalles Bibliográficos
Autores principales: Buschke, Susanne, Stark, Hans-Jürgen, Cerezo, Ana, Prätzel-Wunder, Silke, Boehnke, Karsten, Kollar, Jasmin, Langbein, Lutz, Heldin, Carl-Henrik, Boukamp, Petra
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057703/
https://www.ncbi.nlm.nih.gov/pubmed/21289094
http://dx.doi.org/10.1091/mbc.E10-11-0879