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A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes
The mechanism by which transforming growth factor-β (TGFβ) regulates differentiation in human epidermal keratinocytes is still poorly understood. To assess the role of Smad signaling, we engineered human HaCaT keratinocytes either expressing small interfering RNA against Smads2, 3, and 4 or overexp...
Autores principales: | Buschke, Susanne, Stark, Hans-Jürgen, Cerezo, Ana, Prätzel-Wunder, Silke, Boehnke, Karsten, Kollar, Jasmin, Langbein, Lutz, Heldin, Carl-Henrik, Boukamp, Petra |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057703/ https://www.ncbi.nlm.nih.gov/pubmed/21289094 http://dx.doi.org/10.1091/mbc.E10-11-0879 |
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