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Activation of Colicin M by the FkpA Prolyl Cis-Trans Isomerase/Chaperone

Colicin M (Cma) is specifically imported into the periplasm of Escherichia coli and kills the cells. Killing depends on the periplasmic peptidyl prolyl cis-trans isomerase/chaperone FkpA. To identify the Cma prolyl bonds targeted by FkpA, we replaced the 15 proline residues individually with alanine...

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Detalles Bibliográficos
Autores principales: Helbig, Stephanie, Patzer, Silke I., Schiene-Fischer, Cordelia, Zeth, Kornelius, Braun, Volkmar
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057819/
https://www.ncbi.nlm.nih.gov/pubmed/21149455
http://dx.doi.org/10.1074/jbc.M110.165274