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Noninvasive multi–photon fluorescence microscopy resolves retinol and retinal–condensation products in mouse eyes
Multi–photon excitation fluorescence microscopy (MPM) can image certain molecular processes in vivo. In the eye, fluorescent retinyl esters in sub–cellular structures called retinosomes mediate regeneration of the visual chromophore, 11–cis–retinal, by the visual cycle. But harmful fluorescent conde...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057900/ https://www.ncbi.nlm.nih.gov/pubmed/21076393 http://dx.doi.org/10.1038/nm.2260 |