A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity

BACKGROUND: Thermophilic enzymes are often less active than their mesophilic homologues at low temperatures. One hypothesis to explain this observation is that the extra stabilizing interactions increase the rigidity of thermophilic enzymes and hence reduce their activity. Here we employed a thermop...

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Detalles Bibliográficos
Autores principales: Lam, Sonia Y., Yeung, Rachel C. Y., Yu, Tsz-Ha, Sze, Kong-Hung, Wong, Kam-Bo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057955/
https://www.ncbi.nlm.nih.gov/pubmed/21423654
http://dx.doi.org/10.1371/journal.pbio.1001027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057955/
https://www.ncbi.nlm.nih.gov/pubmed/21423654
http://dx.doi.org/10.1371/journal.pbio.1001027

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