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Calcium/Calmodulin Dependent Protein Kinase II Bound to NMDA Receptor 2B Subunit Exhibits Increased ATP Affinity and Attenuated Dephosphorylation

Calcium/calmodulin dependent protein kinase II (CaMKII) is implicated to play a key role in learning and memory. NR2B subunit of N-methyl-D-aspartate receptor (NMDAR) is a high affinity binding partner of CaMKII at the postsynaptic membrane. NR2B binds to the T-site of CaMKII and modulates its catal...

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Detalles Bibliográficos
Autores principales: Cheriyan, John, Kumar, Parimal, Mayadevi, Madhavan, Surolia, Avadhesha, Omkumar, Ramakrishnapillai V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057968/
https://www.ncbi.nlm.nih.gov/pubmed/21423658
http://dx.doi.org/10.1371/journal.pone.0016495