Whole-Blood Flow-Cytometric Analysis of Antigen-Specific CD4 T-Cell Cytokine Profiles Distinguishes Active Tuberculosis from Non-Active States

T-cell based IFN-γ release assays do not permit distinction of active tuberculosis (TB) from successfully treated disease or latent M. tuberculosis infection. We postulated that IFN-γ and IL-2 cytokine profiles of antigen-specific T cells measured by flow-cytometry ex vivo might correlate with TB di...

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Detalles Bibliográficos
Autores principales: Sester, Urban, Fousse, Mathias, Dirks, Jan, Mack, Ulrich, Prasse, Antje, Singh, Mahavir, Lalvani, Ajit, Sester, Martina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058054/
https://www.ncbi.nlm.nih.gov/pubmed/21423578
http://dx.doi.org/10.1371/journal.pone.0017813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058054/
https://www.ncbi.nlm.nih.gov/pubmed/21423578
http://dx.doi.org/10.1371/journal.pone.0017813

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