Cargando…

Whole-Blood Flow-Cytometric Analysis of Antigen-Specific CD4 T-Cell Cytokine Profiles Distinguishes Active Tuberculosis from Non-Active States

T-cell based IFN-γ release assays do not permit distinction of active tuberculosis (TB) from successfully treated disease or latent M. tuberculosis infection. We postulated that IFN-γ and IL-2 cytokine profiles of antigen-specific T cells measured by flow-cytometry ex vivo might correlate with TB di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sester, Urban, Fousse, Mathias, Dirks, Jan, Mack, Ulrich, Prasse, Antje, Singh, Mahavir, Lalvani, Ajit, Sester, Martina
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058054/ https://www.ncbi.nlm.nih.gov/pubmed/21423578 http://dx.doi.org/10.1371/journal.pone.0017813

Ejemplares similares

Antigen-Specific CD4 T Cells Are Induced after Intravesical BCG-Instillation Therapy in Patients with Bladder Cancer and Show Similar Cytokine Profiles as in Active Tuberculosis
por: Elsäßer, Julia, et al.
Publicado: (2013)

Alterations in pathogen-specific cellular and humoral immunity associated with acute peripheral facial palsy of infectious origin
por: Mohammad, Leyla, et al.
Publicado: (2023)

VZV-specific T-cell levels in patients with rheumatic diseases are reduced and differentially influenced by antirheumatic drugs
por: Schub, David, et al.
Publicado: (2018)

A Polyclonal Immune Function Assay Allows Dose-Dependent Characterization of Immunosuppressive Drug Effects but Has Limited Clinical Utility for Predicting Infection on an Individual Basis
por: Marx, Stefanie, et al.
Publicado: (2020)

Levels of CMV Specific CD4 T Cells Are Dynamic and Correlate with CMV Viremia after Allogeneic Stem Cell Transplantation
por: Widmann, Thomas, et al.
Publicado: (2008)

Case report: cerebral sinus vein thrombosis in two patients with AstraZeneca SARS-CoV-2 vaccination
por: Fousse, Mathias, et al.
Publicado: (2021)

A multicenter, randomized, open-labeled study to steer immunosuppressive and antiviral therapy by measurement of virus (CMV, ADV, HSV)-specific T cells in addition to determination of trough levels of immunosuppressants in pediatric kidney allograft recipients (IVIST01-trial): study protocol for a randomized controlled trial
por: Ahlenstiel-Grunow, Thurid, et al.
Publicado: (2014)

Calcineurin inhibitors differentially alter the circadian rhythm of T-cell functionality in transplant recipients
por: Leyking, Sarah, et al.
Publicado: (2015)

Cellular immunity predominates over humoral immunity after homologous and heterologous mRNA and vector-based COVID-19 vaccine regimens in solid organ transplant recipients
por: Schmidt, Tina, et al.
Publicado: (2021)

Treatment of Cytomegalovirus Infection with Cidofovir and CMV Immune Globulin in a Lung Transplant Recipient
por: Wilkens, Heinrike, et al.
Publicado: (2016)

Cytomegalovirus-specific T-cell responses and viral replication in kidney transplant recipients
por: Egli, Adrian, et al.
Publicado: (2008)

Boosting immunity after CoronaVac
por: Sester, Martina, et al.
Publicado: (2022)

Is ipsilateral administration of COVID-19 vaccine boosters the optimal approach?
por: Ziegler, Laura, et al.
Publicado: (2023)

Differences in SARS-CoV-2 specific humoral and cellular immune responses after contralateral and ipsilateral COVID-19 vaccination
por: Ziegler, Laura, et al.
Publicado: (2023)

NVX-CoV2373-induced cellular and humoral immunity towards parental SARS-CoV-2 and VOCs compared to BNT162b2 and mRNA-1273-regimens
por: Hielscher, Franziska, et al.
Publicado: (2022)

Novel human sex-typing strategies based on the autism candidate gene NLGN4X and its male-specific gametologue NLGN4Y
por: Maxeiner, Stephan, et al.
Publicado: (2019)

Calcium homeostasis in red blood cells of dialysis patients in dependence of erythropoietin treatment
por: Wang, Jue, et al.
Publicado: (2014)

T-Cell Immunophenotyping Distinguishes Active From Latent Tuberculosis
por: Pollock, Katrina M., et al.
Publicado: (2013)

High levels of SARS-CoV-2–specific T cells with restricted functionality in severe courses of COVID-19
por: Schub, David, et al.
Publicado: (2020)

Impact of COVID-19 in solid organ transplant recipients
por: Danziger-Isakov, Lara, et al.
Publicado: (2021)

Bioengineering of Anti‐Inflammatory Natural Products
por: Winand, Lea, et al.
Publicado: (2020)

Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination
por: Schmidt, Tina, et al.
Publicado: (2021)

Transient Positive SARS-CoV-2 PCR without Induction of Systemic Immune Responses
por: Gärtner, Barbara C., et al.
Publicado: (2023)

Simultaneous flow cytometric analysis of human T cell activation antigen expression and DNA content
Publicado: (1983)

Comparative immunogenicity and reactogenicity of heterologous ChAdOx1-nCoV-19-priming and BNT162b2 or mRNA-1273-boosting with homologous COVID-19 vaccine regimens
por: Klemis, Verena, et al.
Publicado: (2022)

Clinical Application of Interferon-γ Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence
por: Lange, Christoph, et al.
Publicado: (2017)

Numerical modelling of label-structured cell population growth using CFSE distribution data
por: Luzyanina, Tatyana, et al.
Publicado: (2007)

Microfluidic implementation of functional cytometric microbeads for improved multiplexed cytokine quantification
por: Liu, Ya, et al.
Publicado: (2018)

The meta-analysis for ideal cytokines to distinguish the latent and active TB infection
por: Wei, Zhenhong, et al.
Publicado: (2020)

Side scatter versus CD45 flow cytometric plot can distinguish acute leukaemia subtypes
por: Saksena, Annapurna, et al.
Publicado: (2016)

Assay for ADAMTS-13 Activity with Flow Cytometric Readout
por: Müller, Jens, et al.
Publicado: (2022)

Evaluating the clinical impact of routine whole genome sequencing in tuberculosis treatment decisions and the issue of isoniazid mono-resistance
por: Park, Mirae, et al.
Publicado: (2022)

Standardization and reference ranges for whole blood platelet function measurements using a flow cytometric platelet activation test
por: Huskens, Dana, et al.
Publicado: (2018)

Predicting progression to active tuberculosis: A rate-limiting step on the path to elimination
por: Lalvani, Ajit, et al.
Publicado: (2019)

Case Report: Management of a Multidrug-Resistant CMV-Strain in a Renal Transplant Recipient by High-Dose CMV-Specific Immunoglobulins, Modulation in Immunosuppression, and Induction of CMV-Specific Cellular Immunity
por: Wiening, Vanessa, et al.
Publicado: (2021)

Flow Cytometric Investigation of Classical and Alternative Platelet Activation Markers
por: Nagy, Béla, et al.
Publicado: (2013)

Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides
por: Yazıcı, Serkan, et al.
Publicado: (2015)

A Novel Image Cytometric Method for Quantitation of Immunohistochemical Staining of Cytoplasmic Antigens
por: Guillaud, M., et al.
Publicado: (1997)

The CDC crossmatch in the era of flow cytometric cross-match and single antigen beads
por: Mahowald, Grace Kao
Publicado: (2021)

Biosynthetic Plasticity Enables Production of Fluorinated Aurachins
por: Sester, Angela, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_src42vg5gk06gbndodo9vpb22m