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Single Nucleotide Polymorphisms of TCF7L2 Are Linked to Diabetic Coronary Atherosclerosis

BACKGROUND: Coronary artery disease (CAD) shares common risk factors with type 2 diabetes (T2DM). Variations in the transcription factor 7-like 2 (TCF7L2) gene, particularly rs7903146, increase T2DM risk. Potential links between genetic variants of the TCF7L2 locus and coronary atherosclerosis are u...

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Detalles Bibliográficos
Autores principales: Muendlein, Axel, Saely, Christoph H., Geller-Rhomberg, Simone, Sonderegger, Gudrun, Rein, Philipp, Winder, Thomas, Beer, Stefan, Vonbank, Alexander, Drexel, Heinz
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058059/
https://www.ncbi.nlm.nih.gov/pubmed/21423583
http://dx.doi.org/10.1371/journal.pone.0017978