Cargando…

Single Nucleotide Polymorphisms of TCF7L2 Are Linked to Diabetic Coronary Atherosclerosis

BACKGROUND: Coronary artery disease (CAD) shares common risk factors with type 2 diabetes (T2DM). Variations in the transcription factor 7-like 2 (TCF7L2) gene, particularly rs7903146, increase T2DM risk. Potential links between genetic variants of the TCF7L2 locus and coronary atherosclerosis are u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Muendlein, Axel, Saely, Christoph H., Geller-Rhomberg, Simone, Sonderegger, Gudrun, Rein, Philipp, Winder, Thomas, Beer, Stefan, Vonbank, Alexander, Drexel, Heinz
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058059/ https://www.ncbi.nlm.nih.gov/pubmed/21423583 http://dx.doi.org/10.1371/journal.pone.0017978

Ejemplares similares

Roles of the Metabolic Syndrome, HDL Cholesterol, and Coronary Atherosclerosis in Subclinical Inflammation
por: Rein, Philipp, et al.
Publicado: (2010)

Genome-Wide Association Study Reveals a Polymorphism in the Podocyte Receptor RANK for the Decline of Renal Function in Coronary Patients
por: Leiherer, Andreas, et al.
Publicado: (2014)

Are SGLT2 polymorphisms linked to diabetes mellitus and cardiovascular disease? Prospective study and meta-analysis
por: Drexel, Heinz, et al.
Publicado: (2019)

Serotonin is elevated in risk-genotype carriers of TCF7L2 - rs7903146
por: Leiherer, Andreas, et al.
Publicado: (2019)

Coronary patients with high plasma omentin are at a higher cardiovascular risk
por: Saely, Christoph H., et al.
Publicado: (2015)

Insulin resistance is significantly associated with the metabolic syndrome, but not with sonographically proven peripheral arterial disease
por: Vonbank, Alexander, et al.
Publicado: (2013)

Identification of Hypoxia-Induced Genes in Human SGBS Adipocytes by Microarray Analysis
por: Geiger, Kathrin, et al.
Publicado: (2011)

Plasma 1-deoxysphingolipids are predictive biomarkers for type 2 diabetes mellitus
por: Othman, Alaa, et al.
Publicado: (2015)

A common variant of the MACC1 gene is significantly associated with overall survival in colorectal cancer patients
por: Lang, Alois H, et al.
Publicado: (2012)

Data on the association between CTRP1 and future major adverse cardiovascular events in patients undergoing coronary angiography
por: Muendlein, Axel, et al.
Publicado: (2019)

Type 2 diabetes and the risk of cardiovascular events in peripheral artery disease versus coronary artery disease
por: Sprenger, Lukas, et al.
Publicado: (2021)

Single and joint impact of type 2 diabetes and of congestive heart failure on albuminuria: Data from subgroup analysis and data on moderate albuminuria
por: Saely, Christoph H., et al.
Publicado: (2022)

CD14 C-159T and Toll-Like Receptor 4 Asp299Gly Polymorphisms in Surviving Meningococcal Disease Patients
por: Biebl, Ariane, et al.
Publicado: (2009)

Serum uromodulin is associated with impaired glucose metabolism
por: Leiherer, Andreas, et al.
Publicado: (2017)

Data on the power of the creatinine to uromodulin ratio in serum to predict cardiovascular events in coronary patients
por: Leiherer, Andreas, et al.
Publicado: (2017)

Toward a more professional and practical medical education: a novel Central European approach
por: Drexel, Heinz, et al.
Publicado: (2015)

Value of total cholesterol readings earlier versus later in life to predict cardiovascular risk
por: Leiherer, Andreas, et al.
Publicado: (2021)

Quercetin Impacts Expression of Metabolism- and Obesity-Associated Genes in SGBS Adipocytes
por: Leiherer, Andreas, et al.
Publicado: (2016)

Downhill hiking improves low-grade inflammation, triglycerides, body weight and glucose tolerance
por: Drexel, Heinz, et al.
Publicado: (2021)

Hypoxia induces a HIF-1α dependent signaling cascade to make a complex metabolic switch in SGBS-adipocytes()
por: Leiherer, Andreas, et al.
Publicado: (2014)

Data on the association of serum glypican-4 with future major adverse cardiovascular events and mortality in patients undergoing coronary angiography
por: Muendlein, Axel, et al.
Publicado: (2022)

Evaluation of the association of serum glypican-4 with prevalent and future kidney function
por: Muendlein, Axel, et al.
Publicado: (2022)

Bile Acid Metabolites in Serum: Intraindividual Variation and Associations with Coronary Heart Disease, Metabolic Syndrome and Diabetes Mellitus
por: Steiner, Carine, et al.
Publicado: (2011)

Unrecognized High Occurrence of Genetically Confirmed Hereditary Carnitine Palmitoyltransferase II Deficiency in an Austrian Family Points to the Ongoing Underdiagnosis of the Disease
por: Zach, Christina, et al.
Publicado: (2019)

Coronary Event Risk Test (CERT) as a Risk Predictor for the 10-Year Clinical Outcome of Patients with Peripheral Artery Disease
por: Leiherer, Andreas, et al.
Publicado: (2023)

Data on the impact of peripheral artery disease and of type 2 diabetes mellitus on the risk of cardiovascular events
por: Saely, Christoph H., et al.
Publicado: (2018)

Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients
por: Muendlein, Axel, et al.
Publicado: (2021)

Circulating syndecan-1 and glypican-4 predict 12-month survival in metastatic colorectal cancer patients
por: Muendlein, Axel, et al.
Publicado: (2022)

Circulating microRNAs -192 and -194 are associated with the presence and incidence of diabetes mellitus
por: Jaeger, Andrea, et al.
Publicado: (2018)

Data on the power of high betatrophin to predict cardiovascular deaths in coronary patients
por: Leiherer, Andreas, et al.
Publicado: (2019)

Role of the single nucleotide polymorphism rs7903146 of TCF7L2 in inducing nonsense-mediated decay
por: Nicod, Nathalie, et al.
Publicado: (2014)

Association of Single Nucleotide Polymorphisms in TCF2 with Type 2 Diabetes Susceptibility in a Han Chinese Population
por: Zhang, Xuelong, et al.
Publicado: (2012)

Association between Lipid Levels, Anti-SARS-CoV-2 Spike Antibodies and COVID-19 Mortality: A Prospective Cohort Study
por: Mink, Sylvia, et al.
Publicado: (2023)

Effects of the diabetes linked TCF7L2 polymorphism in a representative older population
por: Melzer, David, et al.
Publicado: (2006)

TF and TCF4 gene polymorphisms are linked to autism spectrum disorder: a case–control study
por: Azmerin, Maria, et al.
Publicado: (2022)

Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis
por: Vargas, Jose D., et al.
Publicado: (2016)

Anti-SARS-CoV-2 antibody levels predict outcome in COVID-19 patients with type 2 diabetes: a prospective cohort study
por: Mink, Sylvia, et al.
Publicado: (2023)

Selection of single-nucleotide polymorphisms in disease association data
por: Joo, Jungnam, et al.
Publicado: (2005)

SARS-CoV-2 RBD-specific and NP-specific antibody response of healthcare workers in the westernmost Austrian state Vorarlberg: a prospective cohort study
por: Atzl, Michele, et al.
Publicado: (2022)

Individualisierung der antihypertensiven Therapie bei Patient:innen mit Diabetes mellitus. Leitlinie der Österreichischen Diabetes Gesellschaft (Update 2023)
por: Saely, Christoph H., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e6egs5p3i96pmqp1hehrv2mv4g