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β(2)-microglobulin forms 3D domain-swapped amyloid fibrils with disulfide linkages
β(2)-microglobulin (β(2)m) is the light chain of type I major histocompatibility complex. It deposits as amyloid fibrils within joints during long-term hemodialysis treatment. Despite the devastating effects of dialysis-related amyloidosis, full understanding of how fibrils form from soluble β(2)m r...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058263/ https://www.ncbi.nlm.nih.gov/pubmed/21131979 http://dx.doi.org/10.1038/nsmb.1948 |