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Programmable in situ amplification for multiplexed imaging of mRNA expression

In situ hybridization methods enable the mapping of mRNA expression within intact biological samples 1,2. With current approaches, it is challenging to simultaneously map multiple target mRNAs within whole-mount vertebrate embryos 3–6 – a significant limitation in attempting to study interacting reg...

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Detalles Bibliográficos
Autores principales: Choi, Harry M.T., Chang, Joann Y., Trinh, Le A., Padilla, Jennifer E., Fraser, Scott E., Pierce, Niles A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058322/
https://www.ncbi.nlm.nih.gov/pubmed/21037591
http://dx.doi.org/10.1038/nbt.1692