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Transcription of functionally related constitutive genes is not coordinated

Expression of an individual gene can vary considerably among genetically identical cells due to stochastic fluctuations in transcription. However proteins comprising essential complexes or pathways have similar abundances and lower variability. It is not known whether coordination in the expression...

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Detalles Bibliográficos
Autores principales: Gandhi, Saumil J., Zenklusen, Daniel, Lionnet, Timothee, Singer, Robert H.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058351/
https://www.ncbi.nlm.nih.gov/pubmed/21131977
http://dx.doi.org/10.1038/nsmb.1934