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Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons
Parkinson’s disease is a neurodegenerative disorder characterized by severe motor deficits mainly due to degeneration of dopaminergic neurons in the substantia nigra. Decreased levels of the cell’s most important anti-oxidant, glutathione, have been detected in nigral neurons of Parkinson patients,...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058355/ https://www.ncbi.nlm.nih.gov/pubmed/21191602 http://dx.doi.org/10.1007/s00401-010-0791-x |