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HCN Channelopathy in External Globus Pallidus Neurons in Models of Parkinson’s Disease
Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by a profound motor disability that is traceable to the emergence of synchronous, rhythmic spiking in neurons of the external segment of the globus pallidus (GPe). The origins of this pathophysiology are poorly defined. Fo...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058391/ https://www.ncbi.nlm.nih.gov/pubmed/21076425 http://dx.doi.org/10.1038/nn.2692 |