HCN Channelopathy in External Globus Pallidus Neurons in Models of Parkinson’s Disease

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by a profound motor disability that is traceable to the emergence of synchronous, rhythmic spiking in neurons of the external segment of the globus pallidus (GPe). The origins of this pathophysiology are poorly defined. Fo...

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Detalles Bibliográficos
Autores principales: Chan, C. Savio, Glajch, Kelly E., Gertler, Tracy S., Guzman, Jaime N., Mercer, Jeff N., Lewis, Alan S., Goldberg, Alan B., Tkatch, Tatiana, Shigemoto, Ryuichi, Fleming, Sheila M., Chetkovich, Dane M., Osten, Pavel, Kita, Hitoshi, Surmeier, D. James
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058391/
https://www.ncbi.nlm.nih.gov/pubmed/21076425
http://dx.doi.org/10.1038/nn.2692

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