ROLE OF RAC-1 DEPENDENT NADPH OXIDASE IN THE GROWTH OF PANCREATIC CANCER

K-ras mutations occur in as high as 95% of patients with pancreatic cancer. K-ras activates Rac1-dependent NADPH oxidase, a key source of superoxide. Superoxide plays an important role in pancreatic cancer cell proliferation and scavenging or decreasing the levels of superoxide inhibits pancreatic c...

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Detalles Bibliográficos
Autores principales: Du, Juan, Liu, Jingru, Smith, Brian J., Tsao, Ming-Sound, Cullen, Joseph J.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058504/
https://www.ncbi.nlm.nih.gov/pubmed/21037555
http://dx.doi.org/10.1038/cgt.2010.64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058504/
https://www.ncbi.nlm.nih.gov/pubmed/21037555
http://dx.doi.org/10.1038/cgt.2010.64

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