Quantitative reactivity profiling predicts functional cysteines in proteomes

Cysteine is the most intrinsically nucleophilic amino acid in proteins, where its reactivity is tuned to perform diverse biochemical functions. The absence of a consensus sequence that defines functional cysteines in proteins has hindered their discovery and characterization. Here, we describe a pro...

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Detalles Bibliográficos
Autores principales: Weerapana, Eranthie, Wang, Chu, Simon, Gabriel M., Richter, Florian, Khare, Sagar, Dillon, Myles B.D., Bachovchin, Daniel A., Mowen, Kerri, Baker, David, Cravatt, Benjamin F.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058684/
https://www.ncbi.nlm.nih.gov/pubmed/21085121
http://dx.doi.org/10.1038/nature09472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058684/
https://www.ncbi.nlm.nih.gov/pubmed/21085121
http://dx.doi.org/10.1038/nature09472

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