Reduced Rif2 and no Mec1 targets short telomeres for elongation rather than double-strand break repair

S. cerevisiae telomerase binds and preferentially elongates short telomeres, events that require the checkpoint kinase Tel1. We show that the Mre11 complex bound preferentially to short telomeres, which can explain the preferential binding of Tel1 to these ends. Compared to wild type length telomere...

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Detalles Bibliográficos
Autores principales: McGee, Jean S., Phillips, Jane A., Chan, Angela, Sabourin, Michelle, Paeschke, Katrin, Zakian, Virginia A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058685/
https://www.ncbi.nlm.nih.gov/pubmed/21057524
http://dx.doi.org/10.1038/nsmb.1947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058685/
https://www.ncbi.nlm.nih.gov/pubmed/21057524
http://dx.doi.org/10.1038/nsmb.1947

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