Iron-Catalyzed Oxidation Intermediates Captured in a DNA Repair Dioxygenase

Mononuclear iron-containing oxygenases conduct a diverse variety of oxidation functions in biology1,2, including the oxidative demethylation of methylated nucleic acids and histones3,4. E. coli AlkB is the first such enzyme that was discovered to repair methylated nucleic acids (Fig. 1)5,6, which ar...

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Detalles Bibliográficos
Autores principales: Yi, Chengqi, Jia, Guifang, Hou, Guanhua, Dai, Qing, Zhang, Wen, Zheng, Guanqun, Jian, Xing, Yang, Cai-Guang, Cui, Qiang, He, Chuan
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058853/
https://www.ncbi.nlm.nih.gov/pubmed/21068844
http://dx.doi.org/10.1038/nature09497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058853/
https://www.ncbi.nlm.nih.gov/pubmed/21068844
http://dx.doi.org/10.1038/nature09497

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