Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission

Mitochondria are dynamic organelles that undergo cycles of fission and fusion. The yeast dynamin-related protein, Dnm1, has been localized to sites of mitochondrial division. Using cryo-electron microscopy (cryo-EM), we have determined the three-dimensional structure of Dnm1 in a GTP-bound state. Th...

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Detalles Bibliográficos
Autores principales: Mears, Jason A., Lackner, Laura L., Fang, Shunming, Ingerman, Elena, Nunnari, Jodi, Hinshaw, Jenny E.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059246/
https://www.ncbi.nlm.nih.gov/pubmed/21170049
http://dx.doi.org/10.1038/nsmb.1949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059246/
https://www.ncbi.nlm.nih.gov/pubmed/21170049
http://dx.doi.org/10.1038/nsmb.1949

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