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Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission
Mitochondria are dynamic organelles that undergo cycles of fission and fusion. The yeast dynamin-related protein, Dnm1, has been localized to sites of mitochondrial division. Using cryo-electron microscopy (cryo-EM), we have determined the three-dimensional structure of Dnm1 in a GTP-bound state. Th...
Autores principales: | Mears, Jason A., Lackner, Laura L., Fang, Shunming, Ingerman, Elena, Nunnari, Jodi, Hinshaw, Jenny E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059246/ https://www.ncbi.nlm.nih.gov/pubmed/21170049 http://dx.doi.org/10.1038/nsmb.1949 |
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