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A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris

BACKGROUND: Pichia pastoris is one of the most important host organisms for the recombinant production of proteins in industrial biotechnology. To date, strain specific parameters, which are needed to set up feeding profiles for fed batch cultivations, are determined by time-consuming continuous cul...

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Detalles Bibliográficos
Autores principales: Dietzsch, Christian, Spadiut, Oliver, Herwig, Christoph
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059269/
https://www.ncbi.nlm.nih.gov/pubmed/21371310
http://dx.doi.org/10.1186/1475-2859-10-14