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A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris
BACKGROUND: Pichia pastoris is one of the most important host organisms for the recombinant production of proteins in industrial biotechnology. To date, strain specific parameters, which are needed to set up feeding profiles for fed batch cultivations, are determined by time-consuming continuous cul...
Autores principales: | Dietzsch, Christian, Spadiut, Oliver, Herwig, Christoph |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059269/ https://www.ncbi.nlm.nih.gov/pubmed/21371310 http://dx.doi.org/10.1186/1475-2859-10-14 |
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