Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression

BACKGROUND: Less than 30% of malignant gliomas respond to adjuvant chemotherapy. Here, we have asked whether variations in the constitutive expression of early-growth response factor 1 (EGR-1) predicted acute cytotoxicity and clonogenic cell death in vitro, induced by six different chemotherapics. M...

Descripción completa

Detalles Bibliográficos
Autores principales: Calogero, Antonella, Porcellini, Antonio, Lombari, Vincenza, Fabbiano, Cinzia, Arcella, Antonietta, Miscusi, Massimo, Ponti, Donatella, Ragona, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059282/
https://www.ncbi.nlm.nih.gov/pubmed/21366897
http://dx.doi.org/10.1186/1475-2867-11-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059282/
https://www.ncbi.nlm.nih.gov/pubmed/21366897
http://dx.doi.org/10.1186/1475-2867-11-5

Ejemplares similares