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Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression
BACKGROUND: Less than 30% of malignant gliomas respond to adjuvant chemotherapy. Here, we have asked whether variations in the constitutive expression of early-growth response factor 1 (EGR-1) predicted acute cytotoxicity and clonogenic cell death in vitro, induced by six different chemotherapics. M...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059282/ https://www.ncbi.nlm.nih.gov/pubmed/21366897 http://dx.doi.org/10.1186/1475-2867-11-5 |