Mre11–Rad50–Xrs2 and Sae2 promote 5’ strand resection of DNA double-strand breaks

The repair of DNA double-strand breaks by homologous recombination is essential for genomic stability. The first step in this process is resection of 5’ strands to generate 3’ single-stranded DNA intermediates. Efficient resection in budding yeast requires the Mre11–Rad50–Xrs2 (MRX) complex and the...

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Detalles Bibliográficos
Autores principales: Nicolette, Matthew L., Lee, Kihoon, Guo, Zhi, Rani, Mridula, Chow, Julia M., Lee, Sang Eun, Paull, Tanya T.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059534/
https://www.ncbi.nlm.nih.gov/pubmed/21102445
http://dx.doi.org/10.1038/nsmb.1957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059534/
https://www.ncbi.nlm.nih.gov/pubmed/21102445
http://dx.doi.org/10.1038/nsmb.1957

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