The Orphan Nuclear Receptor Nurr1 Restricts the Proliferation of Hematopoietic Stem Cells

Successful hematopoiesis requires long-term retention of the quiescent state of hematopoietic stem cells (HSCs). The transcriptional regulation of stem cell quiescence, especially by factors with specific functions in HSCs, is only beginning to be understood. Here we demonstrate that Nurr1, a nuclea...

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Detalles Bibliográficos
Autores principales: Sirin, Olga, Lukov, Georgi, Mao, Rui, Conneely, Orla, Goodell, Margaret A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059561/
https://www.ncbi.nlm.nih.gov/pubmed/21076412
http://dx.doi.org/10.1038/ncb2125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059561/
https://www.ncbi.nlm.nih.gov/pubmed/21076412
http://dx.doi.org/10.1038/ncb2125

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