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The HDAC Inhibitor Phenylbutyrate Reverses Effects of Neonatal Ventral Hippocampal Lesion in Rats

Recent evidence suggests that epigenetic mechanisms play a role in psychiatric diseases. In this study, we considered rats with neonatal ventral hippocampal lesions (NVHL) that are currently used for modeling neurodevelopmental aspects of schizophrenia. Contribution of epigenetic regulation to the e...

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Detalles Bibliográficos
Autores principales: Sandner, Guy, Host, Lionel, Angst, Marie-Josée, Guiberteau, Thierry, Guignard, Blandine, Zwiller, Jean
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059629/
https://www.ncbi.nlm.nih.gov/pubmed/21423460
http://dx.doi.org/10.3389/fpsyt.2010.00153