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Anti-Inflammatory Impact of Minocycline in a Mouse Model of Tauopathy

Alzheimer's disease (AD) is characterized by the extracellular deposition of β-amyloid in senile plaques, the intraneuronal accumulation of hyperphosphorylated tau aggregates as neurofibrillary tangles, and progressive neuronal loss leading to the onset of dementia. Increasing evidence suggests...

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Detalles Bibliográficos
Autores principales: Garwood, Claire J., Cooper, Jonathan D., Hanger, Diane P., Noble, Wendy
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059645/
https://www.ncbi.nlm.nih.gov/pubmed/21423446
http://dx.doi.org/10.3389/fpsyt.2010.00136