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Questions about STDP as a General Model of Synaptic Plasticity

According to spike-timing-dependent plasticity (STDP), the timing of the Na(+) spike relative to the EPSP determines whether LTP or LTD will occur. Here, we review our reservations about STDP. Most investigations of this process have been done under conditions in which the spike is evoked by postsyn...

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Detalles Bibliográficos
Autores principales: Lisman, John, Spruston, Nelson
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059684/
https://www.ncbi.nlm.nih.gov/pubmed/21423526
http://dx.doi.org/10.3389/fnsyn.2010.00140