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Genetic Controls Balancing Excitatory and Inhibitory Synaptogenesis in Neurodevelopmental Disorder Models

Proper brain function requires stringent balance of excitatory and inhibitory synapse formation during neural circuit assembly. Mutation of genes that normally sculpt and maintain this balance results in severe dysfunction, causing neurodevelopmental disorders including autism, epilepsy and Rett syn...

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Detalles Bibliográficos
Autores principales: Gatto, Cheryl L., Broadie, Kendal
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059704/
https://www.ncbi.nlm.nih.gov/pubmed/21423490
http://dx.doi.org/10.3389/fnsyn.2010.00004