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The E3 ubiquitin ligase Wwp2 regulates craniofacial development through monoubiquitination of Goosecoid

Craniofacial anomalies (CFA) are the most frequent human congenital disease and a major cause of infant mortality and childhood morbidity. Although CFA appear to arise from a combination of genetic factors and environmental influences, the underlying gene defects and pathomechanisms for the majority...

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Detalles Bibliográficos
Autores principales: Zou, Weiguo, Chen, Xi, Shim, Jae, Huang, Zhiwei, Brady, Nicholas, Hu, Dorothy, Drapp, Rebecca, Sigrist, Kirsten, Glimcher, Laurie H., Jones, Dallas
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059716/
https://www.ncbi.nlm.nih.gov/pubmed/21170031
http://dx.doi.org/10.1038/ncb2134