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The E3 ubiquitin ligase Wwp2 regulates craniofacial development through monoubiquitination of Goosecoid
Craniofacial anomalies (CFA) are the most frequent human congenital disease and a major cause of infant mortality and childhood morbidity. Although CFA appear to arise from a combination of genetic factors and environmental influences, the underlying gene defects and pathomechanisms for the majority...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059716/ https://www.ncbi.nlm.nih.gov/pubmed/21170031 http://dx.doi.org/10.1038/ncb2134 |