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Determinants of laminin polymerization revealed by the structure of the α5 chain amino-terminal region
The polymerization of laminin into a cell-associated network—a key step in basement membrane assembly—is mediated by the laminin amino-terminal (LN) domains at the tips of the three short arms of the laminin αβγ-heterotrimer. The crystal structure of a laminin α5LN–LE1–2 fragment shows that the LN d...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059903/ https://www.ncbi.nlm.nih.gov/pubmed/21311558 http://dx.doi.org/10.1038/embor.2011.3 |