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Development of Epoxyeicosatrienoic Acid Analogs with in Vivo Anti-Hypertensive Actions
Epoxyeicosatrienoic acids (EETs) contribute importantly to the regulation of vascular tone and blood pressure control. The purpose of this study was to develop stable EET analogs and test their in vivo blood pressure lowering effects in hypertensive rats. Using the pharmacophoric moiety of EETs, eth...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059925/ https://www.ncbi.nlm.nih.gov/pubmed/21423396 http://dx.doi.org/10.3389/fphys.2010.00157 |