Development of Epoxyeicosatrienoic Acid Analogs with in Vivo Anti-Hypertensive Actions

Epoxyeicosatrienoic acids (EETs) contribute importantly to the regulation of vascular tone and blood pressure control. The purpose of this study was to develop stable EET analogs and test their in vivo blood pressure lowering effects in hypertensive rats. Using the pharmacophoric moiety of EETs, eth...

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Detalles Bibliográficos
Autores principales: Imig, John D., Elmarakby, Ahmed, Nithipatikom, Kasem, Wei, Shouzou, Capdevila, Jorge H., Tuniki, Venugopal Raju, Sangras, Bhavani, Anjaiah, Siddam, Manthati, Vijaya L., Sudarshan Reddy, D., Falck, John R.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059925/
https://www.ncbi.nlm.nih.gov/pubmed/21423396
http://dx.doi.org/10.3389/fphys.2010.00157

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