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Cyclooxygenase-2 Inhibition Restored Endothelium-Mediated Relaxation in Old Obese Zucker Rat Mesenteric Arteries

Metabolic syndrome is associated with reduced endothelial vasodilator function. It is also associated with the induction of cyclooxygenase-2 (COX2), which produces vasoactive prostanoids. The frequency of metabolic syndrome increases with age and aging per se is a risk factor associated with reduced...

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Detalles Bibliográficos
Autores principales: Vessières, Emilie, Belin de Chantemèle, Eric J., Toutain, Bertrand, Guihot, Anne-Laure, Jardel, Alain, Loufrani, Laurent, Henrion, Daniel
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059951/
https://www.ncbi.nlm.nih.gov/pubmed/21423385
http://dx.doi.org/10.3389/fphys.2010.00145