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Gene Expression Alterations in Immune System Pathways in the Thymus after Exposure to Immunosuppressive Chemicals
BACKGROUND: Dysregulation of positive and negative selection, antigen presentation, or apoptosis in the thymus can lead to immunosuppression or autoimmunity. Diethylstilbestrol (DES), dexamethasone (DEX), cyclophosphamide (CPS), and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are immunosuppressive ch...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060001/ https://www.ncbi.nlm.nih.gov/pubmed/21041162 http://dx.doi.org/10.1289/ehp.1002358 |