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Quantifying the Underestimation of Relative Risks from Genome-Wide Association Studies

Genome-wide association studies (GWAS) have identified hundreds of associated loci across many common diseases. Most risk variants identified by GWAS will merely be tags for as-yet-unknown causal variants. It is therefore possible that identification of the causal variant, by fine mapping, will iden...

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Detalles Bibliográficos
Autores principales: Spencer, Chris, Hechter, Eliana, Vukcevic, Damjan, Donnelly, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060077/
https://www.ncbi.nlm.nih.gov/pubmed/21437273
http://dx.doi.org/10.1371/journal.pgen.1001337