Expanded CAG/CTG Repeat DNA Induces a Checkpoint Response That Impacts Cell Proliferation in Saccharomyces cerevisiae

Repetitive DNA elements are mutational hotspots in the genome, and their instability is linked to various neurological disorders and cancers. Although it is known that expanded trinucleotide repeats can interfere with DNA replication and repair, the cellular response to these events has not been cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Sundararajan, Rangapriya, Freudenreich, Catherine H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060079/
https://www.ncbi.nlm.nih.gov/pubmed/21437275
http://dx.doi.org/10.1371/journal.pgen.1001339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060079/
https://www.ncbi.nlm.nih.gov/pubmed/21437275
http://dx.doi.org/10.1371/journal.pgen.1001339

Ejemplares similares