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Bacillus anthracis Protease InhA Increases Blood-Brain Barrier Permeability and Contributes to Cerebral Hemorrhages

Hemorrhagic meningitis is a fatal complication of anthrax, but its pathogenesis remains poorly understood. The present study examined the role of B. anthracis-secreted metalloprotease InhA on monolayer integrity and permeability of human brain microvasculature endothelial cells (HBMECs) which consti...

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Detalles Bibliográficos
Autores principales: Mukherjee, Dhritiman V., Tonry, Jessica H., Kim, Kwang Sik, Ramarao, Nalini, Popova, Taissia G., Bailey, Charles, Popov, Serguei, Chung, Myung-Chul
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060093/
https://www.ncbi.nlm.nih.gov/pubmed/21437287
http://dx.doi.org/10.1371/journal.pone.0017921