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Cooperative Nuclear Localization Sequences Lend a Novel Role to the N-Terminal Region of MSH6

Human mismatch repair proteins MSH2-MSH6 play an essential role in maintaining genetic stability and preventing disease. While protein functions have been extensively studied, the substantial amino-terminal region (NTR*) of MSH6 that is unique to eukaryotic proteins, has mostly evaded functional cha...

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Detalles Bibliográficos
Autores principales: Gassman, Natalie R., Clodfelter, Jill E., McCauley, Anita K., Bonin, Keith, Salsbury, Freddie R., Scarpinato, Karin D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060103/
https://www.ncbi.nlm.nih.gov/pubmed/21437237
http://dx.doi.org/10.1371/journal.pone.0017907