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Cooperative Nuclear Localization Sequences Lend a Novel Role to the N-Terminal Region of MSH6
Human mismatch repair proteins MSH2-MSH6 play an essential role in maintaining genetic stability and preventing disease. While protein functions have been extensively studied, the substantial amino-terminal region (NTR*) of MSH6 that is unique to eukaryotic proteins, has mostly evaded functional cha...
Autores principales: | Gassman, Natalie R., Clodfelter, Jill E., McCauley, Anita K., Bonin, Keith, Salsbury, Freddie R., Scarpinato, Karin D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060103/ https://www.ncbi.nlm.nih.gov/pubmed/21437237 http://dx.doi.org/10.1371/journal.pone.0017907 |
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