The Strain-Encoded Relationship between PrP(Sc) Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease

Prion strains are characterized by differences in the outcome of disease, most notably incubation period and neuropathological features. While it is established that the disease specific isoform of the prion protein, PrP(Sc), is an essential component of the infectious agent, the strain-specific rel...

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Detalles Bibliográficos
Autores principales: Ayers, Jacob I., Schutt, Charles R., Shikiya, Ronald A., Aguzzi, Adriano, Kincaid, Anthony E., Bartz, Jason C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060105/
https://www.ncbi.nlm.nih.gov/pubmed/21437239
http://dx.doi.org/10.1371/journal.ppat.1001317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060105/
https://www.ncbi.nlm.nih.gov/pubmed/21437239
http://dx.doi.org/10.1371/journal.ppat.1001317

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