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Reliable transgene-independent method for determining Sleeping Beauty transposon copy numbers

BACKGROUND: The transposon-based gene delivery technique is emerging as a method of choice for gene therapy. The Sleeping Beauty (SB) system has become one of the most favored methods, because of its efficiency and its random integration profile. Copy-number determination of the delivered transgene...

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Detalles Bibliográficos
Autores principales: Kolacsek, Orsolya, Krízsik, Virág, Schamberger, Anita, Erdei, Zsuzsa, Apáti, Ágota, Várady, György, Mátés, Lajos, Izsvák, Zsuzsanna, Ivics, Zoltán, Sarkadi, Balázs, Orbán, Tamás I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060107/
https://www.ncbi.nlm.nih.gov/pubmed/21371313
http://dx.doi.org/10.1186/1759-8753-2-5