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Multiple Helminth Infection of the Skin Causes Lymphocyte Hypo-Responsiveness Mediated by Th2 Conditioning of Dermal Myeloid Cells

Infection of the mammalian host by schistosome larvae occurs via the skin, although nothing is known about the development of immune responses to multiple exposures of schistosome larvae, and/or their excretory/secretory (E/S) products. Here, we show that multiple (4x) exposures, prior to the onset...

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Detalles Bibliográficos
Autores principales: Cook, Peter C., Aynsley, Sarah A., Turner, Joseph D., Jenkins, Gavin R., Van Rooijen, Nico, Leeto, Mosiuoa, Brombacher, Frank, Mountford, Adrian P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060168/
https://www.ncbi.nlm.nih.gov/pubmed/21445234
http://dx.doi.org/10.1371/journal.ppat.1001323